鑲$エ浠g爜(688575)
鎼滅储

涓浗鎴愪汉濂虫€MH鍙傝€冭寖鍥村缓绔嬬殑澶氫腑蹇冪爺绌

鍙戣〃鏃堕棿锛?023-12-27

鏈爺绌舵槸棣栨浣跨敤鍥戒骇鍙戝厜AMH璇曞墏杩涜涓浗浜虹兢鍙傝€冨尯闂村缓绔嬬殑澶氫腑蹇冪爺绌躲€傞鍏堝娣卞湷甯備簹杈夐緳鐢熺墿绉戞妧鑲′唤鏈夐檺鍏徃鐨刬Flash 3000鍖栧鍙戝厜鍏嶇柅鍒嗘瀽浠娴婣MH鐨勫熀纭€鎬ц兘杩涜璇勪及鍜岄獙璇侊紝骞朵笌杩涘彛鍘傚鍙戝厜AMH璇曞墏杩涜鏂规硶瀛︽瘮瀵广€傜粨鏋滄樉绀篿Flash 3000妫€娴婣MH鍏锋湁鑹ソ鐨勫垎鏋愭€ц兘锛屽叾绌虹櫧闄愪负0.001 ng/mL銆佹鍑洪檺涓?.02 ng/mL銆佸畾閲忛檺涓?.08 ng/mL銆佺嚎鎬ц寖鍥翠负0.02-27.22 ng/mL锛涗綆娴撳害鍜岄珮娴撳害鏃剁殑閲嶅鎬с€佷腑闂寸簿瀵嗗害鍜屾€讳笉绮惧瘑搴﹀潎琛ㄧ幇浼樺紓锛涘湪涓嶅悓鍌ㄥ瓨鏃堕棿鍜屾俯搴︿笅鍧囧叿鏈夎緝濂界殑绋冲畾鎬э紱妫€娴嬬粨鏋滀笌杩涘彛鍙戝厜璇曞墏鍏锋湁鑹ソ鐨勪竴鑷存€с€傜爺绌跺叡绾冲叆1089渚嬩腑鍥芥垚浜哄仴搴峰コ鎬э紝骞舵寜骞撮緞娈靛垎缁勶紙20-24宀併€?5-29宀併€?0-34宀併€?5-39宀併€?0-44宀併€?5-49宀佸拰鈮?0宀侊級寤虹珛澶氫腑蹇冨弬鑰冨尯闂淬€傜粨鏋滆〃鏄嶢MH姘村钩娌℃湁鍦板尯宸紓锛屾垚浜哄コ鎬MH涓綅鍊奸殢鐫€骞撮緞鐨勫鍔犺€岄檷浣庯紝浠?0-24宀佺殑3.98ng/mL闄嶈嚦45-49宀佺殑0.15ng/mL锛?9宀佷互鍚嶢MH涓綅鍊间负0.05ng/mL銆傞€氳繃鍥炲綊妯″瀷鍒嗘瀽涔熻〃鏄庯紝琛€娓匒MH鐨勬祿搴﹂殢鐫€骞撮緞鐨勫闀胯€屼笅闄嶃€
鏌ョ湅璇︽儏

鎶戝埗绱燘鍗曠嫭鎴栬仈鍚堝叾浠栨縺绱犳寚鏍囧湪鐢锋€т笉鑲蹭腑鐨勪复搴婂簲鐢ㄤ环鍊肩爺绌

鍙戣〃鏃堕棿锛?023-12-27

鎶戝埗绱燘锛圛NHB锛夌敱鐢锋€х澗涓告垚鐔熺殑鏀寔缁嗚優鍒嗘硨锛屽彲鍙嶆槧鐢锋€х澗涓哥殑鐢熺簿鍔熻兘銆傛湰澶氫腑蹇冪爺绌剁撼鍏ヤ簡324渚嬩笉鍚岀簿瀛愬彂鐢熺姸鎬佺殑涓浗鐢锋€э紝閲囩敤娣卞湷甯備簹杈夐緳鐢熺墿绉戞妧鑲′唤鏈夐檺鍏徃鐨刬Flash 3000鍖栧鍙戝厜鍏嶇柅鍒嗘瀽浠強閰嶅璇曞墏瀵笽NHB銆佹姉缂嫆姘忕婵€绱狅紙AMH锛夈€佸嵉娉″埡婵€绱狅紙FSH锛夈€佺澗閰紙T锛夌瓑涓冮」鐢熸畺婵€绱犳寚鏍囪繘琛屾娴嬨€傜爺绌跺彂鐜帮紝姝e父缁勪笌灏戠簿瀛愮棁缁勬瘮杈冿紝INHB鐨勬埅鏂€间负97.1 pg/mL锛屾晱鎰熸€у拰鐗瑰紓鎬у垎鍒负79.2%鍜?2.7%锛屽崟椤规娴嬩腑INHB璇婃柇浠峰€兼渶浣炽€傚湪灏戠簿瀛愮棁鎮h€呬腑锛孖NHB璇婃柇涓ラ噸灏戠簿瀛愮棁鐨勬埅鏂€间负58.25 pg/mL锛岄槼鎬ч娴嬪€硷紙PPV锛変负80.65%锛岄槾鎬ч娴嬪€硷紙NPV锛変负58.82%銆傚湪鏃犵簿瀛愮棁鎮h€呬腑锛孖NHB璇婃柇姊楅樆鎬ф棤绮惧瓙鐥囦笌闈炴闃绘€ф棤绮惧瓙鐥囩殑鎴柇鍊间负45.9 pg/mL锛屾晱鎰熸€у拰鐗瑰紓鎬у垎鍒负92.6%鍜?8.3%锛孭PV涓 97.70%锛孨PV涓?5.71%銆傛澶栵紝鐮旂┒杩樺垎鏋愪簡AMH/T鐨勬瘮鍊肩敤浜庨壌鍒瘖鏂闃绘€ф棤绮惧瓙鐥囦笌闈炴闃绘€ф棤绮惧瓙鐥囩殑浠峰€硷紝寰楀嚭AMH/T鐨勬瘮鍊肩殑鎴柇鍊间负1.14锛屾晱鎰熸€у拰鐗瑰紓鎬у垎鍒负89.5%鍜?3.6%锛孯OC鏇茬嚎涓嬮潰绉綆浜嶪NHB锛?.728 vs 0.941锛
鏌ョ湅璇︽儏

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鍙戣〃鏃堕棿锛?023-12-27

鎶楃吉鍕掓皬绠℃縺绱狅紙AMH锛夋槸鎸囧崡鎺ㄨ崘鐨勭敤浜庤瘎浼板嵉宸㈠偍澶囧姛鑳藉拰棰勬祴鍗靛发鍙嶅簲鎬х殑鏈€浣虫爣蹇楃墿銆?018骞达紝涓滈儴鎴樺尯鎬诲尰闄紙鍘熷崡浜啗鍖哄崡浜€诲尰闄級瀵规繁鍦冲競浜氳緣榫欑敓鐗╃鎶€鑲′唤鏈夐檺鍏徃鍖栧鍙戝厜AMH璇曞墏杩涜鍩虹鎬ц兘璇勪及锛屽苟涓庣綏姘忋€佽礉鍏嬫浖杩涜浜嗘柟娉曞姣斿銆傚€煎緱娉ㄦ剰鐨勬槸锛岃繖鏄叏鐞冮娆¤繘琛屼富娴佸寲瀛﹀彂鍏夋硶AMH妫€娴嬭瘯鍓傞棿鐨勬瘮瀵圭爺绌躲€傜粨鏋滄樉绀猴紝浜氳緣榫欏寲瀛﹀彂鍏堿MH璇曞墏鎵瑰唴绮惧瘑搴︿负2.09锛厏5.85锛咃紝鎵归棿绮惧瘑搴︿负4.54锛厏8.82锛咃紱鏈€浣庢娴嬮檺涓?.022 ng/mL锛屼紭浜庨鏈熴€傚悓鏃朵簹杈夐緳鍖栧鍙戝厜AMH璇曞墏妫€娴嬬粨鏋滀笌缃楁皬銆佽礉鍏嬫浖AMH璇曞墏鍧囧叿鏈夎壇濂界殑涓€鑷存€э紝鍏朵腑涓庣綏姘忕殑骞冲潎鍋忓樊涓?.97%锛屼笌璐濆厠鏇肩殑骞冲潎鍋忓樊涓?.62%銆傚厖鍒嗚瘉鏄庝簹杈夐緳鍖栧鍙戝厜AMH璇曞墏鎬ц兘浼樺紓锛屽彲婊¤冻涓村簥璇婄枟鐨勮姹傘€
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鍩轰簬IVF鍔╁瓡濂虫€т汉缇ょ殑骞撮緞鐗瑰紓鎬т綆AMH姘村钩鐨勫畾涔夊強鐩稿叧濡婂缁撳眬

鍙戣〃鏃堕棿锛?023-12-27

鏈爺绌跺緛闆嗕簡2016骞?鏈堣嚦2018骞?鏈堥棿鍦ㄦ繁鍦冲競濡囧辜淇濆仴闄㈢敓娈栧尰瀛︿腑蹇冩帴鍙椾綋澶栧彈绮撅紙IVF锛夊姪瀛曠殑909鍚嶅コ鎬э紝閲囩敤娣卞湷甯備簹杈夐緳鐢熺墿绉戞妧鑲′唤鏈夐檺鍏徃鐨刬Flash 3000鍖栧鍙戝厜鍏嶇柅鍒嗘瀽浠強閰嶅璇曞墏妫€娴嬭娓匒MH姘村钩銆傜爺绌舵寚鍑鸿娓匒MH姘村钩涓庡勾榫勬垚鍙嶆瘮锛圫pearman r = -0.43锛汸聽<聽0.001锛夛紝骞惰繘涓€姝ュ缓绔嬩簡閽堝鍚勫勾榫勫コ鎬х殑AMH鍙傝€冨尯闂达紝骞跺畾涔夊悇骞撮緞AMH姘村钩鐨勭10鐧惧垎浣嶆暟涓轰綆AMH姘村钩鐨勬埅鏂€笺€備笌浣嶢MH姘村钩鐨勫コ鎬х浉姣旓紝AMH姘村钩楂樹簬绗?0鐧惧垎浣嶆暟鐨勫コ鎬у湪鍗靛发鍙嶅簲鎬ф柟闈㈠叿鏈夎壇濂界殑缁撴灉銆傚湪35宀佷互涓嬬殑鎮h€呬腑锛孉MH姘村钩楂樹簬绗?0鐧惧垎浣嶆暟鐨勫コ鎬ц儦鑳庣Щ妞嶇殑涓村簥濡婂鐜囷紙57%锛夊拰鎸佺画濡婂鐜囷紙51.9锛咃級鍧囨樉钁楅珮浜嶢MH姘村钩浣庝簬绗?0鐧惧垎浣嶆暟鐨勫コ鎬х殑涓村簥濡婂鐜囷紙31.3%锛夊拰鎸佺画濡婂鐜囷紙21.9锛咃級銆傜患涓婏紝IVF鍔╁瓡濂虫€х殑AMH姘村钩浣庝簬骞撮緞鐗瑰畾鐨勭10鐧惧垎浣嶆暟鐨勬埅鏂€煎彲鎻愮ず涓嶈壇濡婂缁撳眬銆
鏌ョ湅璇︽儏
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